스템엑소원 (StemExOne)

Innovation

eMTDΔ4 peptide technology

Mechanism of Action

When peptides are treated on cells, the intracellular calcium (Ca²⁺) concentration instantaneously increases. This activates the calcium-mediated enzyme Calpain, causing the cell membrane to protrude outward and leading to the massive secretion of exosomes (microvesicles) through the 'Outward Budding' mechanism.

Production Environment

Produced in a chemical composition buffer (Serum-free Sucrose Buffer) completely free of animal-derived components (FBS), preventing impurity contamination.

01

Peptide

eMTDΔ4 peptide treatment (Serum-free)

02

Ca²⁺ Influx

Instant increase in intracellular calcium ion concentration

03

Activation

Activation of calcium-mediated enzyme (Calpain)

04

Explosion

Explosive secretion of exosomes (within 15 minutes)

Performance

Overwhelming competitiveness compared to existing methods

Higher Yield Increase

20x

Purity Enhancement

35%

Revolution in productivity and purity

Production has increased over 30 times compared to conventional methods, and purity has improved over 45 times.
This goes beyond mere speed improvement, changing the dimensions of economics and quality.

Comparison Items	Conventional Cultivation Method	ExoCargo (StemExOne)
Time Required	Induction over 24 hours	Ultra-short induction within 15 minutes
Cultivation Environment	Use of animal-derived serum (FBS)	Chemical composition buffer (Serum-free)
Product Purity	Impurity contamination and low purity	Ultra-high purity (contamination source blocked)
Homogeneity	Low homogeneity due to prolonged exposure	Achieving ultra-homogeneity with short induction time

Versatile DDS Cargo
Loading

Unlimited scalability

ExoCargo not only produces a large quantity of exosomes but also serves as a platform for precisely loading desired target substances.

Gene & Protein

Customized exosome production precisely loaded with miRNA, membrane proteins, etc.

Viral Vectors

AAV-loaded exosomes (AAV-Exo) maximize safety and targeting

Small Molecules

Homogeneous and stable mass production of exosomes containing embedded compounds

Therapeutic Potency

Proven anti-inflammatory and regenerative effects

TS-eEVs produced by ExoCargo technology show superior
performance compared to naturally occurring exosomes.

Significant acceleration of wound healing speed
Inhibition of inflammatory cytokines (IL-6, TNF-α)
Excellent skin regeneration and immune modulation capabilities