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ExoFlow4D

High-Yield & High-Performance Exosome Engine

Mass production of highly functional exosomes
through 4D dynamic culture

Innovation

4D Dynamic Cultivation Platform

Evolution of Cultivation Technology: From 2D to 4D We have overcome the planar limitations of existing cultivation methods and implemented an environment similar to that inside the body.

2D Flat Culture
2D 평면 배양

Adhesion-Dependent

Limitations: Different from in vivo environment, limited productivity

3D Suspension Culture
3D 부유 배양

Suspension Culture

(Suspension Culture)

4D Dynamic Cultivation
4D 동적 배양

Physical/Chemical Stimulation
Inducing High-Performance
Exosome Secretion

Platform Process Detailed Description

When stem cells with adhesive growth characteristics are cultured in a suspended state on our developed 4D blood flow mimicking dynamic culture platform, cell surface proteins related to adhesion and penetration are overexpressed, resulting in the generation of cells and cell-derived exosomes with excellent tissue penetration and absorption.

공정 세부 설명 프로세스 이미지
  • Adhesive Protein
    (Magnified View)
  • Cell Surface
  • Stem Cell Active
    Ingredients
  • 3D Blood Flow Mimicking
    Dynamic Culture Reactor
  • Blood Flow Mimicking Platform
    Cultivation Cross-Section
  • Stem Cell 3D
    Aggregates
  • Surface Changes of
    Stem Cell 3D Aggregates
Performance

Productivity and Economic Value

Exosome production per batch increased
by approximately 20 times

20x

Production costs reduced
by approximately 35%

35%

Manufacturing process time reduced
by approximately 30%

30%

Classification Detailed Description Key Achievements
Production Volume Increased exosome production through physical and chemical stimulation Approximately 20 times increase in pure purified exosome production
Cost Cultivation area reduced by about 60%, media consumption reduced by about 40% Production costs reduced by about 35%
Time Reduction in manufacturing process time through dense cell suspension cultivation Manufacturing process time reduced by about 30%
Competitive Edge
Patent-Based Technology

Patent-Based Technology

We have established a technical barrier by completing domestic patent registration for the method of producing extracellular vesicles from three-dimensional cultured stem cells.

[Patent Registration] 10-2020-0051640

Securing Market Advantage

Securing Market Advantage

We can mass-produce high-performance exosomes with excellent skin absorption at a low cost, giving us strong price and quality competitiveness in the cosmetics and therapeutics market.

  • Veterinary Medical Device VexoHeal
  • Stem Cell Cosmetic StemOne Alpha